BBa_K1366109

BBa_K1366109 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K1366109

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Eduardo Cepeda Ca??edo, Mercedes Alejandra Vazquez Cantu

Date created: 2014-10-09 11:00:00

Date modified: 2015-05-08 01:10:08

pep42 peptide

Details

• Types: DnaRegion
• Roles: Coding; CDS
• Sequences: BBa_K1366109_sequence (Version 1)

Description

This part allows the production of a recombinant pIII protein linked with a pep42 peptide. This peptide change the tropism of the virus M13 and enables it to bind to a receptor called GRP78 that it is highly present in cancer cells. The binding between pep42 and GRP78 receptor allows the bacteriophage to penetrate the cancer cells and this initiates the transfection of DNA mediated with bacteriophages.

Notes

The structure of this construct is pIII linked with a pep42 peptide

Source

We used the DNA sequence of the PIII protein that is reported in NCBI

Sequence Annotations

Sequence Annotation	Location	Component / Role(s)
pep42	1,81	CDS, feature/cds

Other Properties

• igem#experience: None
• igem#sampleStatus: It's complicated
• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K1366109/1

Member of these Collections

• iGEM Parts Registry