Types | DnaRegion
|
Roles | promoter
Regulatory
|
Sequences | BBa_K1442025_sequence (Version 1)
|
Description
The aptazyme is a RNA sequence that can be placed into a construct for design purposes (e.g. safety, regulatory), the aptazyme self-cleaves in the presence of theophylline to destroy the construct, preventing translation, transcription etc.
Notes
Optimising the theophylline concentration due to its toxicity that self-cleaving effect will remain.
Source
Synthetically designed sequence