BBa_K1647018

BBa_K1647018 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K1647018
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Yun Xue
Date created: 2015-09-14 11:00:00
Date modified: 2016-02-01 12:50:26

CAP-Bac8c, an improved antimicrobial peptide selectively



Types
DnaRegion

Roles
Composite

engineered_region

Sequences BBa_K1647018_sequence (Version 1)

Description

The CAP is a short peptide derived from the competence stimulation peptide(CSP) which can binding to the receptors on the membrane of the S.mutans selectively. The Bac8c is the strong antimicrobial peptide which can kill the bacterial effectively. The part is a new improved peptide ,based on the fusion of a S.mutans-specific targeting peptide domain with a wide-spectrum antimicrobial peptide domain ,which can restrain even kill the S.mutans specifically.

Notes

To reduce the effect of the CAP on the Bac8c, the CAP only has the least effective sequence of the CSP. Besides, we design an intersequence ,GGG, put between the CAP and Bac8c for the same goal.

Source

None for the moment

igem#experience
None
 
igem#status
Planning
 
synbiohub#ownedBy
user/james
 
synbiohub#ownedBy
user/myers
 
synbiohub#topLevel
BBa_K1647018/1