Types | DnaRegion
|
Roles | Composite
engineered_region
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Sequences | BBa_K1647018_sequence (Version 1)
|
Description
The CAP is a short peptide derived from the competence stimulation peptide(CSP) which can binding to the receptors on the membrane of the S.mutans selectively. The Bac8c is the strong antimicrobial peptide which can kill the bacterial effectively. The part is a new improved peptide ,based on the fusion of a S.mutans-specific targeting peptide domain with a wide-spectrum antimicrobial peptide domain ,which can restrain even kill the S.mutans specifically.
Notes
To reduce the effect of the CAP on the Bac8c, the CAP only has the least effective sequence of the CSP. Besides, we design an intersequence ,GGG, put between the CAP and Bac8c for the same goal.
Source
None for the moment