Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Heming Wang
Date created: 2015-08-25 11:00:00
Date modified: 2015-08-30 07:46:12
LsrA of LuxS/AI-2 signaling pathway in Salmonalla
| Types | DnaRegion |
| Roles | CDS Coding |
| Sequences | BBa_K1666000_sequence (Version 1) |
Description
In a process called quorum sensing, bacteria communicate with one another using secreted chemical signaling molecules termed autoinducers. As the density of the bacterial population increases, so does the concentration of secreted autoinducer molecules. When the concentration of the autoinducer reaches a critical threshold, it diffuses back into the cell and activates or represses certain target genes.An autoinducer called AI-2 is generated by many species of Gram-negative and Gram-positive bacteria. In the LuxS/AI-2 signaling system of Salmonella enterica serovar Typhimurium, AI-2 response involves genes named lsr (LuxS regulated) that encode ATP binding cassette-type transporter. And LsrA is ATP-binding protein of the ABC transporter. In our project, we set this part under a nisA promoter for the final purpose of constructing an integrated AI-2 response pathway in our engineering bacteria.