2 x FYVE

BBa_K1769000 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K1769000

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Ho-Tsang Tsai

Date created: 2015-09-13 11:00:00

Date modified: 2015-09-18 01:21:33

Dimeric FYVE

Details

• Types: DnaRegion
• Roles: Composite; engineered_region
• Sequences: BBa_K1769000_sequence (Version 1)

Description

Dimeric Hrs FYVE is a small binding molecule that can bind to phosphatidylinositol 3-phosphate (PtdIns(3)P), a receptor that exists on endosome. Since it is more stable then monomeric FYVE, it is widely used to recognize and locate PtdIns(3)P.

Notes

The linker region with 6 amino acid between two FYVE protein domain works better

Source

This part come from Hrs gene from mouse

Sequence Annotations

Sequence Annotation	Location	Component / Role(s)
start codon	1,3	start_codon, feature/start
FYVE domain	1,204	feature/cds, CDS
linker region	205,255	feature/cds, CDS
FYVE domain	256,426	sequence_feature, feature/misc

Other Properties

• igem#experience: Issues
• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K1769000/1

Member of these Collections

• iGEM Parts Registry