Types | DnaRegion
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Roles | promoter
Regulatory
|
Sequences | BBa_K179000_sequence (Version 1)
|
Description
XRE works as dioxin sensor when co-expressed with Arnt and Ahr. Dioxin first binds to the Ahr protein, and this Dioxin-Ahr binds to Arnt. The resulting complex in cytosol is then transfered to the nucleus and bind to the XRE sequences, which works as enhancer of downstream promoter.
Notes
To use as a dioxin sensor, you must use this part with Arnt and Ahr protein coding devices.
Source
XRE human genomic sequence