| Types | DnaRegion
|
| Roles | Generator
engineered_region
|
| Sequences | BBa_K1809999_sequence (Version 1)
|
Description
Antifreeze proteins (AFPs) are molecules with the unique property of binding and shaping ice crystals, preventing their growth into relatively large cell-lysing structures (Davies and Sykes 1997). They exhibit a property known as thermal hysteresis, whereby their activity decreases the freezing point of water without changing the melting point. This property allows organisms which produce AFPs to survive colder conditions. Additionally, AFPs have shown biolfilm inhibiting properties, potentially giving them uses in medical applications.
Notes
Codon optimized the sequence for E. coli and to minimize repetitive sequences; removed illegal restriction sites.
Source
Taken from the Atlantic herring Clupea harengus. Pubmed ID: 9521729
