BBa_K1935000

BBa_K1935000 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K1935000

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Emilie Gounin

Date created: 2016-10-07 11:00:00

Date modified: 2016-10-08 10:08:53

nlp22 - neuropeptide-like protein essential for developmental timed sleep

Details

• Types: DnaRegion
• Roles: Coding; CDS
• Sequences: BBa_K1935000_sequence (Version 1)

Description

nlp-22 is involved in embryo development and positive regulation of error-prone translesion synthesis; nlp-22 is expressed in certain interneurons, head, and the ventral nerve cord.
This Neuropeptide-Like Protein is a regulator of Caenorhabditis elegans sleep-like quiescence observed during lethargus. nlp-22 shows cyclical mRNA expression in synchrony with lethargus; it is regulated by LIN-42, an orthologue of the core circadian protein PERIOD; and it is expressed in the two RIA interneurons. nlp-22 and the RIA interneurons are required for normal lethargus quiescence, and forced expression of nlp-22 during active stages causes anachronistic locomotion and feeding quiescence.

Notes

in progress

Source

nlp22 is a gene in Caenorhabditis elegans.

http://www.wormbase.org/species/c_elegans/gene/WBGene00003760#0-9g-3

Sequence Annotations

Sequence Annotation	Location	Component / Role(s)
stop	310,315	feature/stop, stop_codon

Other Properties

• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K1935000/1

Member of these Collections

• iGEM Parts Registry