BBa_K1935022

BBa_K1935022 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K1935022

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Emilie Gounin

Date created: 2016-10-13 11:00:00

Date modified: 2016-10-14 10:26:37

SET-16 promoter in Caenorhabditis elegans

Details

• Types: DnaRegion
• Roles: promoter; Regulatory
• Sequences: BBa_K1935022_sequence (Version 1)

Description

Ceanorhabditis elegans is an organism with a free-methylated cytosine genome. We looked for a worm???s promoter able to be regulated as mammalian CpG island.

pSET-16 is a promoter of Caenorhabditis elegans classified as a HOT (Highly Occupied Target) regions. HOT regions have a rich G-C content that makes them similar to mammalian CpG islands.
Some HOT promoters have been mentioned by Chen and one of them, SET-16 (chromosome 3: 13643462-13643761), controls a non-essential gene.

That???s why we chose it as a target to test epiCRISPR whithout killing the worm.

Notes

in progress

Source

http://www.wormbase.org/species/c_elegans/gene/WBGene00011729#0-9g-3

Other Properties

• igem#experience: None
• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K1935022/1

Member of these Collections

• iGEM Parts Registry