Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: claire raynaud
Date created: 2016-10-10 11:00:00
Date modified: 2016-10-11 03:37:03
CsgA E. Coli coding sequence
| Types | DnaRegion |
| Roles | sequence_feature DNA |
| Sequences | BBa_K1951007_sequence (Version 1) |
Description
CsgA is the major and structural subunit of the curli fimbriae. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius.Curli are the major proteinaceous component of a complex extracellular matrix produced by many Enterobacteriaceae. Curli were first discovered in the late 1980s on Escherichia coli strains that caused bovine mastitis, and have since been implicated in many physiological and pathogenic processes of E. coli and Salmonella spp. Curli fibers are involved in adhesion to surfaces, cell aggregation, and biofilm formation. Curli also mediate host cell adhesion and invasion, and they are potent inducers of the host inflammatory response.
Notes
We modified Pst1 site CTGCAG into CTGCGG.We added prefix and suffix sequences containing restriction sites EcoRI, XbaI and SpeI, PstI respectively.
Source
The coding sequence has been found on the following website :http://www.ncbi.nlm.nih.gov/nuccore/EU554560.1