BBa_K1951010

BBa_K1951010 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K1951010
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: claire raynaud
Date created: 2016-10-12 11:00:00
Date modified: 2016-10-13 02:52:22

CsgA E.coli producer



Types
DnaRegion

Roles
polypeptide_domain

Protein_Domain

Sequences BBa_K1951010_sequence (Version 1)

Description

CsgA is the major and structural subunit of the curli fimbriae. Curli are coiled surface structures that assemble preferentially at growth temperatures below 37 degrees Celsius. Curli are the major proteinaceous component of a complex extracellular matrix produced by many Enterobacteriaceae. Curli were first discovered in the late 1980s on Escherichia coli strains that caused bovine mastitis, and have since been implicated in many physiological and pathogenic processes of E. coli and Salmonella spp. Curli fibers are involved in adhesion to surfaces, cell aggregation, and biofilm formation. Curli also mediate host cell adhesion and invasion, and they are potent inducers of the host inflammatory response.
The biobrick contains a strong promotor.

Notes

CsgA coding sequence has been amplified using slic oligos from the sequence created previously by Lyon igem team 2010.

Source

To make this biobrick, we used previous one :
- Bba_K880005
- Bba_K1951007

igem#status
Planning
 
synbiohub#ownedBy
user/myers
 
synbiohub#ownedBy
user/james
 
synbiohub#topLevel
BBa_K1951010/1