Types | DnaRegion
|
Roles | Coding
CDS
|
Sequences | BBa_K2011000_sequence (Version 1)
|
Description
sgrS (sugar transport-related sRNA, previously named ryaA) is a small RNA that is activated by SgrR in Escherichia coli during glucose-phosphate stress. The nature of glucose-phosphate stress is not fully understood, but is correlated with intracellular accumulation of glucose-6-phosphate. SgrS helps cells recover from glucose-phosphate stress by base pairing with ptsG mRNA (encoding the glucose transporter) and causing its degradation in an RNase E dependent manner. Base pairing between SgrS and ptsG mRNA also requires Hfq, an RNA chaperone frequently required by small RNAs that affect their targets through base pairing.
The sgrS binding site is on the ptsG, which can let sgrS small RNA binds on it.
Notes
no
Source
It's come from BL21(DE3) genomic DNA.