BBa_K2011000

BBa_K2011000 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K2011000
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Po-Ying Huang
Date created: 2016-10-13 11:00:00
Date modified: 2016-10-14 08:00:08

sgrS binding site



Types
DnaRegion

Roles
Coding

CDS

Sequences BBa_K2011000_sequence (Version 1)

Description

sgrS (sugar transport-related sRNA, previously named ryaA) is a small RNA that is activated by SgrR in Escherichia coli during glucose-phosphate stress. The nature of glucose-phosphate stress is not fully understood, but is correlated with intracellular accumulation of glucose-6-phosphate. SgrS helps cells recover from glucose-phosphate stress by base pairing with ptsG mRNA (encoding the glucose transporter) and causing its degradation in an RNase E dependent manner. Base pairing between SgrS and ptsG mRNA also requires Hfq, an RNA chaperone frequently required by small RNAs that affect their targets through base pairing.
The sgrS binding site is on the ptsG, which can let sgrS small RNA binds on it.

Notes

no

Source

It's come from BL21(DE3) genomic DNA.

Sequence Annotation Location Component / Role(s)
sgrS binding site
1,255
engineered_region feature/BioBrick
igem#status
Planning
 
synbiohub#ownedBy
user/james
 
synbiohub#ownedBy
user/myers
 
synbiohub#topLevel
BBa_K2011000/1