BBa_K2068005

BBa_K2068005 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K2068005

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Nithin Dharmaraj

Date created: 2016-09-12 11:00:00

Date modified: 2016-09-13 12:57:21

O3-33 Wild Type

Details

• Types: DnaRegion
• Roles: engineered_region; Generator
• Sequences: BBa_K2068005_sequence (Version 1)

Description

The O3-33 gene codes for the production of one subunit of a protein cage. Each subunit consists of a trimeric protein that is designed to have low-energy protein-protein interfaces. Expression of this subunit will lead to the self assembly of a octahedral structured protein cage.Protein cages, are self assembling supramolecular protein structures where multiple protein subunits interact non covalently to form a higher order structure. This protein cage, O3-33, is a 24 subunit, 13nm diameter cage.

Notes

This cage was computationally designed. The two steps that were crucial in the design of the cage were
1) symmetrical docking of protein building blocks in a target symmetric architecture
2) design of low energy protein-protein interfaces between the protein building blocks to drive self assembly.

Source

This cage is originally designed by Dr.Neil King.

Other Properties

• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K2068005/1

Member of these Collections

• iGEM Parts Registry