| Types | DnaRegion
|
| Roles | Protein_Domain
polypeptide_domain
|
| Sequences | BBa_K2124001_sequence (Version 1)
|
Description
This Serine protease is a component of Cerastes Cerastes (Desert Horned Viper) venom. It recognizes Thrombin cut sites in fibrinogen and upon cleavage converts the fibrinogen to fibrin monomers. The fibrin monomers can then link and begin clot formation in mammals.
Notes
This protein is very small and stabilized by several disulfide bonds. The final construct will be secreted into the periplasmic space with DsbC, a protein that shuffles disfulfide bonds. DsbC will allow the Serine Protease to fold properly with correct disulfide bonding. This will give stable functional protein.
Source
This is from a genomic sequence of Cerastes Cerastes.
