Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Tianhao Li
Date created: 2016-10-12 11:00:00
Date modified: 2016-10-13 07:05:13
human Epidermal Growth Factor(hEGF) with His-tag
| Types | DnaRegion |
| Roles | CDS Coding |
| Sequences | BBa_K2152000_sequence (Version 1) |
Description
Human EGF（epidermal growth factor）is a 6045-Da protein with 53 amino acid residues. It can stimulate cell growth, proliferation and differentiation by binding to its receptor EGFR both in vivo and vitro.There is a phoA signal peptide at the N-terminus, which is a fragment of signal peptide that guides the protein to go across cytomembrane and do not decrease activity of the protein.
His-tag is an amino acid motif in proteins that consists of at least six histidine (His) residues, at the N-terminus of the EGF protein. It is also known as hexa histidine-tag.
This part is in charge of IBD treatment.
Notes
There is a phoA signal peptide at the N-terminus, which is a fragment of signal peptide that guides the protein to go across cytomembrane and do not decrease activity of the protein.His-tag is an amino acid motif in proteins that consists of at least six histidine (His) residues, at the N-terminus of the EGF protein. It is also known as hexa histidine-tag. This tag is used for protein purification.