Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Marc T. K. Nielsen
Date created: 2009-08-02 11:00:00
Date modified: 2015-05-08 01:11:36
RIP - Quorum sensing inhibitor of Staphylococcus spp. (Including MRSA)
| Types | DnaRegion |
| Roles | Coding CDS |
| Sequences | BBa_K237000_sequence (Version 1) |
Description
RIP or RNAIII inhibiting peptide is a heptapeptide capable of severely reducing the Qourum sensing(QS) abilities of Staphylococcus species. RIP effectively works as an antibiotic in its inhibition of bacterial growth.RIP has the sequence YSPXTNF and has been tested extensively in a synthetic (as in organic) form for ability to inhibit bacterial infections in mice.
References will come later.
This is a pure RIP Brick, it contains no signal sequence and we can at this point in our project not verify that it will be exported by our Coli's
Notes
This sequence is reverse-engineered from the amino-acid sequence by using the commonly used codons of E. Coli.It is designed to provide a big output of peptide. We just hope that this output won't kill the cell.