| Types | DnaRegion
|
| Roles | Translational_Unit
engineered_region
|
| Sequences | BBa_K302034_sequence (Version 1)
|
Description
Encodes a stable non-specific ribonuclease toxin and its inhibitory antitoxin in Bacillus Subtilis. These genes are use in Bacillus Subtilis to provide a toxin-antitoxin in various stressful conditions. When transcribtion of both genes is turned off (as both are under contol of same promoter) mazE will be degraded faster than mazF. There is then no inhibiton of mazF, killing the cell.
Notes
Sequence isolated based upon the work of Pellegrini, O., Mathy, N., Gogos, A., Shapiro, L., and Condon, C. (2005) The Bacillus subtilis ydcDE operon encodes an endoribonuclease of the MazF/PemK family and its inhibitor. Mol Microbiol 56: 1139???1148.
Source
Bacillus Subtilis 168 strain
