Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Endre K??roly Krist??f
Date created: 2010-08-09 11:00:00
Date modified: 2015-05-08 01:12:14
hBAX
| Types | DnaRegion |
| Roles | Coding CDS |
| Sequences | BBa_K364202_sequence (Version 1) |
Description
Coding sequence of Bax (Bcl-2-associated X) protein which is a pro-apoptotic meber of the Bcl-2 protein family. It contains four BH (Bcl-2 homology) domains, can form homo- and heterodimers and plays essential role in the formation of MOMP (Mitochondrial outer membrane permeabilization) leading to apoptosis which is the most frequent type of PCD (Programmed cell death).Notes
Compatible with RFC-10 and RFC-25.Source
Human BAX (of the Bcl-2 gene family)| Sequence Annotation | Location | Component / Role(s) |
| BH3 domain BH1 domain BH2 domain Transmembrane domain | 177,219 294,354 450,495 516,573 | sequence_feature feature/misc sequence_feature feature/misc feature/misc sequence_feature sequence_feature feature/misc |