Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Lior Malka
Date created: 2010-09-30 11:00:00
Date modified: 2015-05-08 01:12:14
NHR-23 LBD
| Types | DnaRegion |
| Roles | CDS Coding |
| Sequences | BBa_K364315_sequence (Version 1) |
Description
Nuclear hormone receptor family member nhr-23.The nhr-23 gene encodes a nuclear hormone receptor homolog that is required in all larval molts; NHR-23 is highly similar to Drosophila DHR3, an ecdysone-inducible gene product involved in metamorphosis.
The NHR-23 protein is nuclear, and is present in all blastomeres during early embryogenesis; during later stages of morphogenesis, NHR-23 is restricted to epidermal cells.
nhr-23 expression cycles between stages of larval development; during each intermolt period, levels of nhr-23 transcripts are 2-5 times greater than levels at each molt.
NHR-23 binds the DRS-type hormone response sequence in vitro