Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Brian Burnley
Date created: 2010-10-26 11:00:00
Date modified: 2015-05-08 01:12:16
PYY3-36 (Peptide Tyrosine Tyrosine, 3-36)
| Types | DnaRegion |
| Roles | Coding CDS |
| Sequences | BBa_K373000_sequence (Version 1) |
Description
PYY3-36 is an endogenous hormone produced in the ileum and colon or mammalian species, and postprandially released in proportion to the calories consumed during a meal. The peptide is absorbed into the circulatory system and passes the blood-brain barrier, where it contributes to the regulation of energy homeostasis. Acting as an agonist of the Y2-receptor (a member of the NPY family in the arcuate nucleus of the hypothalamus), PYY3-36 inhibits of gastric motility and reduces appetite.PYY3-36 is intended for use in projects exploring hormonal communication between gut microflora and the central nervous system in mammals.