Types | DnaRegion
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Roles | tag
Tag
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Sequences | BBa_K390003_sequence (Version 1)
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Description
This is the secretion tag on the 5' end of the coding sequence of the pilA gene in Synechocystis sp. PCC 6803. The PilA protein is the major secreted protein in this species (Sergeyenko TV and Los D A. 2000. Identification of secreted proteins of the cyanobacterium Synechocystis sp. strain PCC 6803. FEMS Microbiology Letters 193: 213-216).
In Synechocystis sp. PCC 6803, the system of secretion is based on the charge of the N-terminus leader sequence. Positive charges on the N-terminus leader sequence contribute to secretion in a non-sequence-dependent manner (Sergeyenko TV and Los DA. 2003. Cyanobacterial leader peptides for protein secretion. FEMS Microbiology Letters 218: 351-357).
Notes
none
Source
Based on genomic sequence. Part was created by annealing two oligionucleotides together.