Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Grant Robinson
Date created: 2011-09-26 11:00:00
Date modified: 2015-05-08 01:12:31
pDisplay-Vasopressin-MYC Ligand MammoBlock
| Types | DnaRegion |
| Roles | engineered_region Signalling |
| Sequences | BBa_K511500_sequence (Version 1) |
Description
This part encodes a novel fusion protein that serves to display the arginine vasopressin hormone in the extracellular space of a mammalian cell. This protein consists of the transmembrane domain of the platelet-derived growth factor receptor, the sequence for arginine vasopressin, and the sequence for the MYC epitope. This synthetic ligand was designed for juxtacrine signaling to the arginine vasopressin receptor (AVPR) class, and was specifically designed to function with the AVPR2-TEVs-Gal4-VP16 construct.Notes
Not applicable.Source
This protein includes a human codon-optimized version of the arginine vasopressin sequence, the MYC epitope from the human c-MYC DNA-binding transcription factor, and the transmembrane domain from the murine platelet-derived growth factor receptor.| Sequence Annotation | Location | Component / Role(s) |
| PDGFR Transmembrane Domain MYC Epitope Tag Arginine Vasopressin Murine Ig-Kappa Signal Peptide | 121,270 91,120 64,90 1,63 | feature/protein CDS tag feature/tag non_covalent_binding_site feature/binding tag feature/tag |