| Types | DnaRegion
|
| Roles | promoter
Regulatory
|
| Sequences | BBa_K578001_sequence (Version 1)
|
Description
This is the AT-rich leader region of the CRISPR I array in Escherichia coli str. K-12 substr. MG1655. "Identification and characterization of E. coli CRISPR-cas promoters and their silencing by H-NS" (??. Pul et al, 2010) characterized a single promoter (Pcrispr1) in this sequence. Transcription is silenced through H-NS binding to the leader sequence. Induction requires anti-silencing, either by protein-independent processes, DNA-binding proteins or other modulatory mechanisms not yet identified.
Notes
Determination of the specific region was made according to ??. Pul et al.
Source
Synthesized by IDT. Sequence derived from Escherichia coli str. K-12 substr. MG1655, complete genome (U00096.2) 2876486 to 2876591.
