Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Yu Xiaoyan
Date created: 2011-09-30 11:00:00
Date modified: 2015-05-08 01:12:49
a luxR-type regulator from Sinorhizobium meliloti 1021
| Types | DnaRegion |
| Roles | Coding CDS |
| Sequences | BBa_K594003_sequence (Version 1) |
Description
As the luxR, the sinR can bind with AHLS produced by sinI, and then promotes the expression of sinI, besides, the AHL((C16:1-HSL)is bound to ExpR, forming a complex required for the production of a symbioticallyimportant exopolysaccharide, EPS II. The Rm1021 strain, which normally does not produce EPS II, has an insertion sequence that results in the disruption of expR (a luxR homologue). Strains proficient in EPS II
production, such as Rm41 and Rm8530 (Rm1021 expR?), possess an intact expR gene. ExpR is a positive regulator of the exp genes, which are responsible for EPS II biosynthesis; however, it is unclear whether this regulatory effect is direct or indirect.