BBa_K656000

BBa_K656000 Version 1

Component

Source:
http://parts.igem.org/Part:BBa_K656000
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Evan Clark
Date created: 2011-05-02 11:00:00
Date modified: 2015-05-08 01:13:02

LexA Promoter



Types
DnaRegion

Roles
Regulatory

promoter

Sequences BBa_K656000_sequence (Version 1)

Description

This is the promoter for the LexA gene. LexA is a repressor protein that prevents transcription of the SOS repair pathway unless DNA damage is detected by binding to the SOS genes' promoters and inactivating them. In the presence of single stranded DNA due to DNA damage, another protein, RecA, interacts with ss-DNA. The RecA-ssDNA complex then interacts with LexA, causing it to cleave off the SOS gene promoter, allowing transcription to go forward.

LexA regulates its own promoter

Notes

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Source

E. coli genome

igem#sampleStatus
Not in stock
igem#status
Unavailable
 
synbiohub#ownedBy
user/james
 
synbiohub#ownedBy
user/myers
 
synbiohub#topLevel
BBa_K656000/1