hCG-β

BBa_K732000 Version 1

Component

Source: http://parts.igem.org/Part:BBa_K732000

Generated By: https://synbiohub.org/public/igem/igem2sbol/1

Created by: Joshua Fass

Date created: 2012-09-30 11:00:00

Date modified: 2015-05-08 01:13:06

Human Chorionic Gonadotropin, Beta Subunit (hCG-β
)

Details

• Types: DnaRegion
• Roles: CDS; Coding
• Sequences: BBa_K732000_sequence (Version 1)

Description

Human chorionic gonadotropin (hCG) is a hormone produced during pregnancy. Its beta subunit (hCG-β) contains epitopes recognized by pregnancy tests. The full hCG dimer is also used as an ovulation inducer and can stimulate the production of testosterone in men.

This sequence can be used to express hCG for any downstream uses, and also as an output signal since it triggers pregnancy tests at low concentrations when properly folded.

Notes

Added BioBrick prefix and suffix to native human protein-coding sequence.

Source

The sequence of hCG-beta in the human genome has been known since 1980, and the physical DNA was acquired from a plasmid from the Vogelstein lab through addgene.org.

Other Properties

• igem#experience: Fails
• igem#sampleStatus: It's complicated
• igem#status: Planning
• synbiohub#ownedBy: user/james
• synbiohub#ownedBy: user/myers
• synbiohub#topLevel: BBa_K732000/1

Member of these Collections

• iGEM Parts Registry