Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Amna Sohail
Date created: 2013-06-19 11:00:00
Date modified: 2015-05-08 01:13:49
Fibroblast Growth Factor Receptor Substrate 2
| Types | DnaRegion |
| Roles | Coding CDS |
| Sequences | BBa_K976001_sequence (Version 1) |
Description
The Fibroblast Growth Factor Receptor Substrate 2, or FRS2 protein is a lipid based membrane-anchored docking protein that forms a fusion protein complex with the Fibroblast Growth Factor Receptor-1 (FGFR-1) to regulate downstream signal transduction. In melanocytes, this docking protein mediates signal transduction to pathways as the MAPK pathway that are involved in melanocyte proliferation, differentiation, and migration. FRS2 may be useful in its ability to mediate downstream signaling as the FGF2 ligand binds to FGFR-1.Notes
No particular design considerations were dealt with.Source
Source:UniProt Database
Organism:
Homo sapiens