Types | DnaRegion
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Roles | CDS
Coding
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Sequences | BBa_M11006_sequence (Version 1)
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Description
This gene, which composes part of the arsenic resistance system of several microorganisms, is responsible for the coding of an enzyme which reduces arsenate (ars(V) with a +5 oxidation state) to arsenite (ars(III) with a +3 oxidation state). This is an important step in cell recognition and binding of arsenic ions as most arsenic resistance proteins within microorganisms interact best with arsenite rather than arsenate. This gene could be useful in arsenic detection and binding experiments as it would allow all present arsenic to assume a single, more easily detectable/bindable form, recognizable by common arsenic binding proteins such as ArsR.
Notes
The sequence of this gene was not altered in any way from the reference sequence given by NCBI accession number NP_756163.
Source
This particular form of ArsC was isolated from Escherichia coli strain CFT073. Sequence obtained from NCBI accession NP_756163.