Types | DnaRegion
|
Roles | promoter
Regulatory
|
Sequences | BBa_M36145_sequence (Version 1)
|
Description
This promoter is up-regulated by lowering temperature (to 33 degree Celsius) and it was found in CHO cells. It has been discovered so far that the transcription factors for this promoter are NF-kB and SP1 which are endogenous to both CHO cells and HeLa cells.
Notes
This sequence was found in CHO cells. In other types of cell, it is not guaranteed that the promoter will be up-regulated by the lowering of the temperature.
Source
http://ukpmc.ac.uk/articles/PMC3118111/pdf/1472-6750-11-51.pdf