Types | DnaRegion
|
Roles | Regulatory
promoter
|
Sequences | BBa_M36265_sequence (Version 1)
|
Description
Quorum sensing is a system bacteria use to coordinate behaviors that correlate to cell density. Each species of bacteria produces and senses a unique, diffusable small molecule. This allows bacteria to "count" how many cells of their species are in the vicinity. Pseudomonas Aeruginosa, an opportunistic human pathogen associated with cystic fibrosis, uses two quorum sensing systems, with one of them being LasI/LasR. When LasR interacts with N-(3-oxododecanoyl)-homoserine lactone which is produced by LasI, the complex binds to the promoter of the qsc102 gene and increases expression.
Notes
N/A
Source
The promoter sequence was obtained from Figure 3 of this paper: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC95443/pdf/jb005529.pdf