Types | DnaRegion
|
Roles | Coding
CDS
|
Sequences | BBa_M36624_sequence (Version 1)
|
Description
This part codes for AFP, an antifungal protein produced naturally by Aspergillus giganteus, a mold species in the fungi kingdom. It appears to be involved in the inhibition of chitin synthesis, chitin being a key protein in the cell walls of fungi. It may also have other anti-fungal functions, but more research is necessary to determine its exact mode of action.
Notes
The pre-protein is 94 amino acids long, but is cleaved before secretion into a 51 amino acid peptide that is now active. This part is for the 51 amino acid peptide plus a start codon. We have another part for the immature 94 amino acid peptide.
Source
http://onlinelibrary.wiley.com/doi/10.1111/j.1432-1033.1990.tb19300.x/full This links to the amino acid sequence, which we then entered into IDT Codon Optimizer to find the optimal corresponding DNA sequence in E. coli.