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Showing 901 - 944 of 944 result(s)
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Public
BBa_K091230
BBa_K091230 Version 1 (Component)
cI promoter+RBS+RFP+TT
Public
BBa_I744111
BBa_I744111 Version 1 (Component)
Tc-driven cI (lambda) generator
Public
BBa_K1647000
BBa_K1647000 Version 1 (Component)
CI operator site with GFP
Public
BBa_J13101
BBa_J13101 Version 1 (Component)
LacI repressed lambda CI generator
Public
PL GFP
BBa_K193000 Version 1 (Component)
GFP reporter regulated by CI.
Public
BBa_K1053300
BBa_K1053300 Version 1 (Component)
PLtetO-1-RBS-cI-DT
Public
BBa_K909004
BBa_K909004 Version 1 (Component)
cI with strong ribosomal binding site
Public
BBa_I719022
BBa_I719022 Version 1 (Component)
cI promoter with GFP reporter
Public
BBa_K1159310
BBa_K1159310 Version 1 (Component)
34 AA flexible linker with C-terminal TEV cleavage site (GGGGS)x5-TEV-site-linker) in RFC[25]
Public
BBa_K648032
BBa_K648032 Version 1 (Component)
Slightly weaker RBS with cI repressor
Public
BBa_K648033
BBa_K648033 Version 1 (Component)
Very weak RBS with cI repressor
Public
BBa_K318509
BBa_K318509 Version 1 (Component)
lacI pL + RBS + cI LVA + TT
Public
Plamda-GFP
BBa_I763011 Version 1 (Component)
promoter lambda (cI regulated) with GFP (+LVA) reporter
Public
BBa_K1707004
BBa_K1707004 Version 1 (Component)
TetR-ssRA repressor with the promoter of cI
Public
BBa_K415011
BBa_K415011 Version 1 (Component)
PtetR : RBS : LuxR : Term : PluxR/cI-OR : RBS : mCherry : Term : Plux/cI-OR : RBS : LuxI
Public
BBa_K077039
BBa_K077039 Version 1 (Component)
cI under control of the plac promotor
Public
BBa_K176017
BBa_K176017 Version 1 (Component)
pCI(R0051)(lambda CI-)->RBS+GFP+T
Public
BBa_K145105
BBa_K145105 Version 1 (Component)
cI under T7 and P<sub>R</sub> dual promotor
Public
BBa_K077019
BBa_K077019 Version 1 (Component)
pluxR with cI (lambda) behind a normal RBS
Public
BBa_I3401
BBa_I3401 Version 1 (Component)
Lambda cI switch input device (B0034.C0051.B0015)
Public
BBa_K584011
BBa_K584011 Version 1 (Component)
Lac-Lux hybrid promotor + CrtEBI + CI repressor + INP
Public
BBa_K611017
BBa_K611017 Version 1 (Component)
cI Lambda Repressor and Promoter Wild Type Control
Public
PLac-LacY-
BBa_I763013 Version 1 (Component)
LacY and cI coding device switched on by IPTG
Public
BBa_I758601
BBa_I758601 Version 1 (Component)
Screen for binding affinity of mutant cI lambda to promotor sites
Public
BBa_I758600
BBa_I758600 Version 1 (Component)
Screen for binding affinity of mutant cI lambda to promotor sites
Public
BBa_K145112
BBa_K145112 Version 1 (Component)
cI under T7 and PR<sub>R</sub> dual promotor
Public
BBa_K177035
BBa_K177035 Version 1 (Component)
cI repressor from E. coli phage lambda (+LVA) under control of RBS.3 (medium)
Public
BBa_K584008
BBa_K584008 Version 1 (Component)
Lambda cI and LuxR regulated hybrid promotor + RBS + MelA + RBS + AFP + term
Public
BBa_K415005
BBa_K415005 Version 1 (Component)
pLux/cI-OR : RBS-mCherry : Term : p(tetR) : RBS-luxR : Term
Public
BO_4344_seq
BO_4344_seq Version 1 (Sequence)

Public
BO_4340_seq
BO_4340_seq Version 1 (Sequence)

Public
BO_4374_seq
BO_4374_seq Version 1 (Sequence)

Public
BO_4354_seq
BO_4354_seq Version 1 (Sequence)

Public
BO_4034_seq
BO_4034_seq Version 1 (Sequence)

Public
BO_4234_seq
BO_4234_seq Version 1 (Sequence)

Public
BO_4134_seq
BO_4134_seq Version 1 (Sequence)

Public
BO_4364_seq
BO_4364_seq Version 1 (Sequence)

Public
BO_4349_seq
BO_4349_seq Version 1 (Sequence)

Public
BO_2434_seq
BO_2434_seq Version 1 (Sequence)

Public
BO_4346_seq
BO_4346_seq Version 1 (Sequence)

Public
BO_4342_seq
BO_4342_seq Version 1 (Sequence)

Public
BO_4634_seq
BO_4634_seq Version 1 (Sequence)

Public
BO_3434_seq
BO_3434_seq Version 1 (Sequence)

Public
Intein_assisted_Bisection_Mapping
Intein_assisted_Bisection_Mapping_collection Version 1 (Collection)
Split inteins are powerful tools for seamless ligation of synthetic split proteins. Yet, their use remains limited because the already intricate split site identification problem is often complicated by the requirement of extein junction sequences. To address this, we augmented a mini-Mu transposon-based screening approach and devised the intein-assisted bisection mapping (IBM) method. IBM robustly revealed clusters of split sites on five proteins, converting them into AND or NAND logic gates. We further showed that the use of inteins expands functional sequence space for splitting a protein. We also demonstrated the utility of our approach over rational inference of split sites from secondary structure alignment of homologous proteins. Furthermore, the intein inserted at an identified site could be engineered by the transposon again to become partially chemically inducible, and to some extent enabled post-translational tuning on host protein function. Our work offers a generalizable and systematic route towards creating split protein-intein fusions and conditional inteins for protein activity control.
Showing 901 - 944 of 944 result(s)
Previous 14 15 16 17 18 19