Types | DnaRegion
|
Roles | Composite
engineered_region
|
Sequences | BBa_K1439008_sequence (Version 1)
|
Description
H4 histone can efficiently mediate gene transfer, it rich in positively charged alkaline amino acids and has the ability to combine with DNA. TAT-PTD contains an 11-amino acid peptide, and these amino acids YGRKKRRQRRR are highly basic, which is crucial for penetrating the plasma membrane. We use linker to link H4 histone and TAT, thus it can seize DNA and take it into cells. Now, it becomes our transfer device.
Notes
We got them form iGEM.
Source
TAT-H4 comes from the BBa_K1439004 and the Terminator comes from BBa_B0015