Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Lei Qiao
Date created: 2012-09-14 11:00:00
Date modified: 2015-05-08 01:13:12
Biofilm formation device. yddV gene with the IPTG inducible promoter.
| Types | DnaRegion |
| Roles | engineered_region Composite |
| Sequences | BBa_K748007_sequence (Version 1) |
Description
Gene yddV is under the regulation of Ptrc promoter (IPTG-inducible). yddV is a Diguanylate Cyclase-Genomic. The product of gene yddV has diguanylate cyclase (DGC) activity. DGC uses 2 GTP to form a Bis-(3???-5???)-cyclic dimeric guanosine monophosphate (c-di-GMP). C-di-GMP is a global second messenger in bacteria. Biofilm formation of E.coli is manipulable by varying c-di-GMP concentrations. When the c-di-GMP level stays low, there is little biofilm and the bacteria is dispersive. High concentrations of c-di-GMP promote bacteria to form more cellulose and fimbriae, which enhances the biofilm formation and decrease the motility of bacteria.Notes
nothing specialSource
de novo synthesis| Access | Instance | Definition |
| public public public public | BBa_R0011 BBa_B0034 BBa_K748003 BBa_B0015 | lacI+pL BBa_B0034 BBa_K748003 BBa_B0015 |