Source:
Generated By: https://synbiohub.org/public/igem/igem2sbol/1
Created by: Amna Sohail
Date created: 2013-06-19 11:00:00
Date modified: 2015-05-08 01:13:49
FGFR-1 + FRS2 Complex
| Types | DnaRegion |
| Roles | engineered_region Composite |
| Sequences | BBa_K976002_sequence (Version 1) |
Description
The Fibroblast Growth Factor Receptor-1 and Fibroblast Growth Factor Receptor Substrate 2 complex comprises a fusion protein complex that has the capability to mediate signal transduction. In melanocytes, this multi-protein complex mediate signal transduction to such pathways as the MAPK pathway, which regulate melanocyte proliferation, migration, and differentiation.Notes
No specific design considerations were dealt with.Source
The FGFR-1 protein sequence has been derived from the Emblem Database. The FRS2 protein sequence has been derived from the UnitProt Database.| Access | Instance | Definition |
| public public | BBa_K976000 BBa_K976001 | FGFR-1 FRS2 |
| Sequence Annotation | Location | Component / Role(s) |
| BBa_K976000 BBa_K976001 | 1,2466 2473,3996 | FGFR-1 FRS2 |